Amidoxime functionalized chitosan for uranium sequestration in vivo

Amidoxime functionalized chitosan for uranium sequestration in vivo

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Amidoxime functionalized chitosan (AC) was recommended as a chelator for uranium sequestration in vivo in this study, and the structure-activity relationship was also explored.Compared with ZnNa3-DTPA, which was a commercial uranium mobilization drug, AC exhibited excellent biocompatibility and uranium 5 Piece Queen Slat Panel Bedroom removal efficiency, whether Collections by injection or orally, which could reduce the amounts of uranium deposited in kidneys and femurs by up to 43.6% and 32.

3%.In particular, ACs still possessed the ability to mobilize uranium in vivo even if administration was delayed for 72 h.